Experts already suspects fat sent signals to the body that could both damage cells. Which leads to cancer, and increase the number of them. Now, the Trinity scientists have been able to show, in Nature Immunology journal, how the body’s cancer-fighting cells get clogged by fat. And they hope to be able to find drug treatments that could restore these “natural killer” cells’ fighting abilities.
The type of cell the body uses to destroy cancerous tissue gets clogged by fat. And stops working, the team, from Trinity College Dublin, found. Obesity is the biggest preventable cause of cancer in the UK after smoking, Cancer Research UK says. Most cancer are cause by excess body weight.
Dr Leo Carlin, from the Cancer Research UK Beatson Institute, said: “Although we know that obesity increases the risk of 13 different types of cancer. We still don’t fully understand the mechanisms underlying the link.
“This study reveals how fat molecules prevent immune cells from properly positioning their tumour-killing machinery, and provides new avenues to investigate treatments. “Many research focus on how tumors grow in order to find metabolic targets to stop them. So, this is a reminder of considering the metabolism of immune cells too.”
To reduce risk of cancer, please follow instructions below:
- Keep a healthy weight
- Stop smoking
- Eat a healthy diet
- Cut back on alcohol
- Avoid sunburn